https://medicalxpress.com/news/2022-04- ... issue.html
by Thamarasee Jeewandara , Medical Xpress
Modern imaging modalities have facilitated a steady progress in medicine and treatment of diseases. Among them, Raman spectroscopy has gained attention for clinical applications as a label-free, non-invasive method to deliver a molecular fingerprint of a sample. Researchers can combine such methods with fiber optic-probes to allow easy-access to a patient's body. However, it is still challenging to acquire images with fiber optic probes. In a new report published in Nature Light: Science & Applications, Wei Yang and a team of scientists, at the Leibniz Institute of Photonic Technology in Germany, developed a fiber optic probe-based Raman imaging system to visualize real-time, molecular, virtual reality data and detect chemical boundaries.
The researchers developed the process around a computer-vision based positional tracking system with photometric stereo and augmented and mixed chemicals for molecular imaging and direct visualization of molecular boundaries of three-dimensional surfaces. The method provided an approach to image large tissue areas in a few minutes, to distinguish clinical tissue-boundaries in a range of biological samples.